Review the literature on homeostatic control of ion channel expression and discuss theoretical ideas about how neurons maintain a target level of activity
after perturbation. Describe the experimental evidence that supports the key theories that you summarize. How might such homeostatic regulation lead to
epilepsy?
In thinking about these ideas, you might find it helpful to start with the review article by Tim O’Leary (https://doi.org/10.1016/j.cophys.2018.01.006).