Part one: Write a summary of each article or resource and describe how each one relates to your PICO
Identify the level of evidence in each article and describe the relative strengths and applicability of the study
to your PICO question by using the AACCN hierarchy of evidence.
Synthesize the evidence from both articles into a statement that supports your PICO question.
Describe any additional evidence that you think will be necessary to support your PICO question.
Finally, describe any gaps in the literature related to the PICO question. 3-4 pages
Part two: Based on the literature search, appraisals, and synthesis, defend either by keeping your PICO
question the same or making changes. If you will make changes to the PICO question, provide the new
version. 1 page
PICO Question: In elderly diabetic adults with stage III diabetic foot ulcers does negative wound
pressure therapy lead to improved healing when compared to standard moist wound therapy?”